BioCentury
PODCAST | Deals

Trends in pharma deals — a BioCentury podcast

Plus: FDA signals flexibility with Precigen decision, and Denali tech among other translational highlights 

August 19, 2025 1:11 AM UTC

BioCentury’s third annual analysis of pharma company deals finds that bispecifics and degraders are in, cell and gene therapies are out, and China is bringing much more than me-too assets to cross-border deals. On the latest BioCentury This Week podcast, BioCentury’s analysts assess a year’s worth of deals between pharmas and biotechs to tease out emerging trends.

The analysts also discuss last week’s FDA approval of a vector-based immunotherapy from Precigen Inc. (NASDAQ:PGEN) to treat a rare respiratory disease and whether the decision will set a precedent of more flexibility for rare disease therapies. They then take stock of recent translational coverage in BioCentury, including a report by Denali Therapeutics Inc. (NASDAQ: DNLI) of a way to avoid a key safety issue of anti-amyloid-targeting mAbs.

BioCentury’s Grand Rounds — Europe will take place in Cambridge, U.K., Sept. 17-19. The conference seeks to bridge academia, industry and investors for breakthrough innovation.