BioCentury

Current Editions

March 31, 2025
Bispecifics for I&I: Bypassing combination complexity

At least 30 companies have bispecific antibodies in development for autoimmune and inflammatory diseases

Product Development

Bearing down in turbulent markets: a Perspective

Why companies should plan

Editor's Commentary

Marks’ ouster plunges FDA into crisis

RFK Jr. pushes out CBER director, one of the last veteran leaders of regulatory agency

Regulation

FDA hit by massive cuts that could lead it to miss PDUFA goals

Cuts devised by acting commissioner with no input from center directors

Regulation

Makary, Bhattacharya confirmed, now the hard part starts

The FDA commissioner and NIH director are taking charge of agencies in crisis

Politics, Policy & Law

Emerging Company Profile

Heranova: Detecting endometriosis in the blood like it’s cancer

The Massachusetts-based company launched a microRNA-based liquid biopsy test for endometriosis, with an eye toward disease monitoring and drug development

Data Byte

Petrelintide up front shatters biotech deal record

At nearly $1.7B, Zealand got $300M more than the prior top cash payment

China deals look beyond cancer

At least eight East-to-West licensing deals outside oncology so far this year

Immunology takeouts led by IgA nephropathy, IBD  

Seven of 11 $1B+ immunology acquisitions focused on two diseases

EMA’s CHMP snubs donanemab, even for APOE4 non-carriers

Lilly to seek re-examination. Also in March meeting, CHMP backs label expansions for Opdivo, Tevimbra and more

Discovery & Translation

Science Spotlight: New insight into LAG3’s checkpoint function

BioCentury’s roundup of translational innovations also includes a blood-based T cell assay for T1D, a degrader using a new E3 ligase, and papers from newcos

Regulation

FDA loses two top oncology leaders

Paul Kluetz and Marc Theoret, deputy directors of the Oncology Center of Excellence, have announced their resignations

Politics, Policy & Law

BIO survey warns tariffs would impede biomedical innovation

Industry is trying to head off sector-specific and country-based tariffs

Finance

Autoimmune play Hillstar takes wing with $67M series A: Finance Report

Plus: Novo Holdings, Jeito lead week’s largest A round for VIB company Augustine — and more

Early lessons from the NewCo Model

Panelists on a Capital Markets Preview webinar from BioCentury and Oppenheimer debate the hottest trend in dealmaking

Biopharma Stock Performers

Use BioCentury's interactive dashboard to view top-performing biopharma stocks for the day and the week.

BioCentury ISSN 1097-7201